DEEP VEIN THROMBOSIS FOLLOWING ACUTE ANTERIOR CRUCIATE LIGAMENT RUPTURE
Abstract
Deep vein thrombosis (DVT) is an uncommon complication following isolated ligamentous knee injuries, such as anterior cruciate ligament (ACL) rupture, particularly in young and otherwise healthy individuals. We report the case of a 38-year-old male who sustained an ACL tear while playing basketball. Two weeks after the injury, during physiotherapy he developed swelling and pain in the left calf. Duplex ultrasonography confirmed thrombosis of the common femoral and popliteal veins. Laboratory findings were within normal limits, except for a mildly elevated D-dimer level. The patient was treated with therapeutic low-molecular-weight heparin (LMWH) and supportive measures. Follow-up imaging at six weeks demonstrated partial venous recanalization. This case highlights that ACL rupture alone may predispose patients to venous thromboembolism (VTE), even in the absence of surgical intervention or traditional risk factors. Early recognition and prompt treatment are essential to prevent potentially life-threatening complications.
Keywords: deep vein thrombosis, ACL, venous thromboembolism, knee trauma.
References
2.Garofalo R, Notarnicola A, Moretti L, Moretti B, Marini S, Castagna A. Deep vein thromboembolism after arthroscopy of the shoulder: two case reports and a review of the literature. BMC Musculoskelet Disord. 2010;11:65. doi:10.1186/1471-2474-11-65.
3.Green D. Risk of future arterial cardiovascular events in patients with idiopathic venous thromboembolism. Hematol Am Soc Hematol Educ Program. 2009;2009(1):259–266. doi:10.1182/asheducation-2009.1.259.
4.Ying P, Ding W, Jiang X, Xue Y, Wang Q, Zhu L. Evaluation of deep vein thrombosis risk factors after arthroscopic posterior cruciate ligament reconstruction: a retrospective observational study. Clin Appl Thromb Hemost. 2021;27:10760296211030556. doi:10.1177/10760296211030556.
5.McLendon K, Goyal A, Attia M. Deep venous thrombosis risk factors. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.
6.Joo YB, Kim YM, Song JH, An BK, Kim YK, Kwon ST. The incidence of deep vein thrombosis after anterior cruciate ligament reconstruction: an analysis using routine ultrasonography of 260 patients. PLoS One. 2022;17(12):e0279136. doi:10.1371/journal.pone.0279136.
7.Kraus Schmitz J, Lindgren V, Janarv PM, Forssblad M, Stålman A. Deep venous thrombosis and pulmonary embolism after anterior cruciate ligament reconstruction: incidence, outcome, and risk factors. Bone Joint J. 2019;101-B(1):34–40. doi:10.1302/0301-620X.101B1.BJJ-2018-0646.R1.
8.Xiong Y, Li X, Lei G, Zeng C, Wei J, Ding X, et al. Anterior cruciate ligament tear increases the risk of venous thromboembolism: a population-based cohort study. Knee Surg Sports Traumatol Arthrosc. 2023;31(5):1805–1814. doi:10.1007/s00167-022-07097-x.
9.Reckelhoff KE, Miller A. Interdisciplinary management of deep vein thrombosis during rehabilitation of acute rupture of the anterior cruciate ligament: a case report. J Chiropr Med. 2014;13(2):121–127. doi:10.1016/j.jcm.2014.06.001.
10.Baumgartner RE, Jones MD, Hame S, McAllister DR. Preoperative deep vein thrombosis following acute anterior cruciate ligament tear: report of three cases. Duke Orthop J. 2017;7(1):30–33.
11.Rahman M. Clinical case commentary: unlocking flexibility—approaches to DVT and knee stiffness in ACL recovery. Examines Phys Med Rehabil. 2024;5(1):EPMR.0005605. doi:10.31031/EPMR.2024.05.0006.