ACUTE MESENTERIC VENOSUS THROMBOSIS IN A PREGNANT WOMAN

  • Aleksandra Eftimova Doctoral Studies in Clinical Medicine, Faculty of Medicine, Ss.Cyril and Methodius University in Skopje, North Macedonia
  • Ana Kocevska Specialized Hospital for Gynecology and Obstetrics "Mother Teresa"-Skopje, North Macedonia, Faculty of Medicine, Ss Cyril and Methodius University in Skopje, North Macedonia
  • Anamarija Shpisikj Pushevska SSpecialized Hospital for Gynecology and Obstetrics "Mother Teresa"-Skopje, North Macedonia, Faculty of Medicine, Ss Cyril and Methodius University in Skopje, North Macedonia
  • Jasmina Chelebieva Specialized Hospital for Gynecology and Obstetrics "Mother Teresa"-Skopje, North Macedonia, Faculty of Medicine, Ss Cyril and Methodius University in Skopje, North Macedonia

Abstract

Mesentric venous thrombosis is a blood clot in one or more of the main veins that squeeze blood from the intestine. Superior mesenterine vein is most commonly involved in the process.  The appearance of MVT is usually rare.  The aim of this study is to identify the incidence and obstetric risk factors. This study will analyse a pregnant woman who appeared with an MVT in the 30th  gestational week. A 33-year-old primigravid woman was admitted to the Special Hospital for Gynecology and Obstetrics "Mother Teresa" in Cair, Skopje during the 35th week of pregnancy. The second day after admission, she complained of more intense abdominal pain, anorexia, vomiting and abdominal dystency that were disproportionate to physical signs.  The entire ileum, part of the yeunum and part of the ascendant colon were gangrenose, and thromboembolism was discovered in the corresponding mesenteric veins. Histopathological analysis also revealed extensive edema, hemorrhagic, inflammatory infiltration and necrosis in the resected intestine and widespread thrombosis in mesenteric venous lumens. Although MVT diagnosis during pregnancy is difficult due to its small incidence and uncharacteristic symptoms, signs and laboratory results, MVT is often the main cause of severe abdominal pain during pregnancy and should be included in the differential diagnosis of pregnant women with acute abdominal pain.


Key words: mesentric venous thrombosis, abdominal pain, pregnancy

References

1.Hmoud B, Singal KA, Kamath SP. Mesenteric Venous Thrombosis. Journal of Clinical and Experimental Hepatology 2014; 4(3), p. 1. 257-263.
2.Clair GD, Beach MJ. Mesentric Ischemia. The New England Journal of Medicine 2016; 374(10), p. 1. 959-968.
3.Kassahun WT, Schulz T, Richter O, Hauss J. Unchanged high mortality rates from acute occlusive intestinal ischemia: six year review. Langenbecks Arch Surg 2008; 393, p. 1. 163-171.
4.Park WM, Gloviczki P, Cherry KJ Jr, et al. Contemporary management of acute mesenteric ischemia: factors associated with survival. J Vasc Surg 2002; 35, p. 1. 445-452.
5.Oldenburg WA, Lau LL, Rodenberg TJ, Edmonds HJ, Burger CD. Acute mesenteric ischemia: a clinical review. Arch Intern Med 2004; 164, p. 1. 1054-1062.
6.Singal KA, Kamath SP, Tefferi A. Mesenteric Venous Thrombosis. Mayo Clinic Proceedings 2013; 88(3), p. 1. 285-294.
7. Rhee RY, Gloviczki P. Mesenteric venous thrombosis. Surgical Clinics North America 1997; 77(2), p. 1. 327-338.
8. Kumar S, Kamath PS. Acute superior mesenteric venous thrombosis: one disease or two? American Journal of Gastroenterology 2003; 98(6), p. 1. 1299-1304.
9. Brunaud L, Antunes L, Collinet-Adler S, et al. Acute mesenteric venous thrombosis: case for nonoperative management. Journal of Vascular Surgery 2001; 34(8), p. 1. 673-679.
10. Acosta S. Epidemiology of mesenteric vascular disease: clinical implications. Seminar of Vascular Surgery 2010; 23(1), p. 1. 4-8.
11. Kumar S, Sarr MG, Kamath PS. Mesenteric venous thrombosis. The New England Journal of Medicine 2001; 345, p. 1. 1683-1688.
12. Kanellopoulou T, Alexopoulou A, Theodossiades G, Koskinas J, Archimandritis AJ. Pylephlebitis: an overview of non-cirrhotic cases and factors related to outcome. Scandinavian journal of infectious diseases 2010; 42, p. 1. 804-811.
13. Brandt LJ, Boley SJ. AGA technical review on intestinal ischemia: American Gastrointestinal Association. Gastroenterology 2000; 118, p. 1. 954-968.
14. Hollingshead M, Burke CT, Mauro MA, Weeks SM, Dixon RG, Jaques PF. Transcatheter thrombolytic therapy for acute mesenteric and portal vein thrombosis. Journal of Vascular and Interventional Radiology 2005; 16(5), p. 1. 651-661.
15. Hirata M, Yano H, Taji T, Shirakata Y. Mesenteric vein thrombosis following impregnation via in vitro fertilization-embryo transfer. World Journal of Gastrointestinal Surgery 2017; 9, p. 1. 209-213.
16. Engelhardt TC, Kerstein MD. Pregnancy and mesenteric venous thrombosis. Southern Medical Journal 1989; 82(11), p. 1. 1441-1443.
17. Giannos A, Stavrou S, Goumalatsos N, Fragkoulidis G, Chra E, Argiropoulos D, et al. Mesenteric cysts and mesenteric venous thrombosis leading to intestinal necrosis in pregnancy managed with laparotomy: a case report and review of the literature. Journal of Medical Case Reports 2017; 11(1), p. 1. 184.
18. Augustin G, Majerovic M. Non-obstetrical acute abdomen during pregnancy. European journal of obstetrics, gynecology, and reproductive biology 2007; 131(1), p. 1. 4-12.
19. Rajesh S, Mukund A, Arora A. Imaging Diagnosis of Splanchnic Venous Thrombosis. Gastroenterology research and practice 2015; 2015, p. 1. 101029.
Published
2023-12-26
How to Cite
EFTIMOVA, Aleksandra et al. ACUTE MESENTERIC VENOSUS THROMBOSIS IN A PREGNANT WOMAN. Journal of Morphological Sciences, [S.l.], v. 6, n. 3, p. 34-38, dec. 2023. ISSN 2545-4706. Available at: <https://jms.mk/jms/article/view/vol6no3-5>. Date accessed: 21 dec. 2024.
Section
Articles