POLYOSTOTIC FIBROUS DYSPLASIA

Smiljana Bundovska; Gordana Antuleska; Aleksandar Petrovski; Elena Peneva

Smiljana Bundovska University Institute of Radiology, Clinic Centar Mother Theresa, Skopje, Faculty of Medicine, Ss Cyril and Methodius University in Skopje, Republic of North Macedonia
Gordana Antuleska University Institute of Radiology, Clinic Centar Mother Theresa, Skopje, Faculty of Medicine, Ss Cyril and Methodius University in Skopje, Republic of North Macedonia
Aleksandar Petrovski Radiology resident, Clinic Centar Mother Theresa, Skopje, Republic of North Macedonia
Elena Peneva University Institute of Radiology, Clinic Centar Mother Theresa, Skopje, Republic of North Macedonia

Abstract

Fibrous dysplasia is a benign skeletal disorder in which the normal bone tissue is replaced by immature fibrous tissue. Polyostotic means that abnormal areas may occur in many bones; often they are confined to one side of the body. Replacement of bone by fibrous tissue may lead to pathologic fractures, uneven growth, and deformity. CT and MRI findings in combination with histopathological results are crucial for the diagnosis of this condition. We present a specific case of a patient with polyostotic fibrous dysplasia and the imaging findings that lead to the final diagnosis.

Keywords: fibrous dysplasia, polyostotic, CT, MRI.

References

1. Feller, L., Wood, N.H., Khammissa, R.A. et al. The nature of fibrous dysplasia. Head Face Med 2009; 5 (22). https://doi.org/10.1186/1746-160X-5-22.
2. Adetayo OA, Salcedo SE, Borad V, Richards SS, Workman AD, Ray AO. Fibrous dysplasia: an overview of disease process, indications for surgical management, and a case report. Eplasty. 2015; 26 (15).
3. Prada EJ, Hassan KH, Brandi ML, Falchetti A. Polyostotic form of fibrous dysplasia in a 13 years old Colombian girl showing clinical and biochemical response to neridronate intravenous therapy. Clin Cases Miner Bone Metab. 2009 Sep; 6(3):264-5.
4. Nicole D. Riddle, Marilyn M. Bui; Fibrous Dysplasia. Arch Pathol Lab Med 2013; 137 (1): 134â€“138. doi: https://doi.org/10.5858/arpa.2012.0013-RS.
5. Parekh, Selene G. MD, MBA; Donthineni-Rao, Rakesh MD; Ricchetti, Eric MD; Lackman, Richard D. MD Fibrous Dysplasia, Journal of the American Academy of Orthopaedic Surgeons 2004;12(5):305-313.
6. DiCaprio, Matthew R. MD1; Enneking, William F. MD2 Fibrous Dysplasia, The Journal of Bone & Joint Surgery: August 2005;87 (8):1848-1864 doi: 10.2106/JBJS.D.02942.
7. Roland D. Chapurlat, Pierre J. Meunier, Fibrous dysplasia of bone, Best Practice & Research Clinical Rheumatology 2020;14(2):385-398. https://doi.org/10.1053/berh.1999.0071.