SQUAMOUS CELL CARCINOMA OF THE CONJUCTIVA-CASE REPORT
Abstract
Presentation of a patient with a squamous cell carcinoma of the conjunctiva on his left eye. A 83-year –old man with a squamous cell carcinoma of the conjunctiva was examined and treated at the University Eye Clinic in Skopje, by the ophthalmologist, after a ophthalmological examination and observation in the small country side-ophthalmology department for a year. Near the temporal limbus at 3 o’clock there was present nodous and white tumorous lesion around 1,4 cm. weath with elevation from the eye surface of 0,5 cm. Around the tumor there was local vascularization. External photographs were taken to document the lesion. The excision biopsy was performed. Topical antibiotic-steroid combination of eye drops was applied 3 times daily for 4 weeks after the primary excision of tumor. The diagnosis was pathohistologically confirmed at the Institute of Pathology in Skopje. Conclusion: Primary excision biopsy is preferably therapy and treatment. Also the primary excision biopsy is a golden standard for proper diagnosis for small squamous cell carcinoma of conjunctiva.Keywords: squamous cell carcinoma, conjunctiva, eye, pathohistology.
Keywords: squamous cell carcinoma, conjunctiva, eye, pathohistology.
References
2. Honavar SG, Manjandavida FP. Tumors of the ocular surface: A review. Indian J Ophthalmol. 2015 Mar;63(3):187-203. doi: 10.4103/0301-4738.156912. PMID: 25971163; PMCID: PMC4448231.
3. Dandala PP, Malladi P, Kavitha. Ocular Surface Squamous Neoplasia (OSSN): A Retrospective Study. J Clin Diagn Res. 2015 Nov;9(11):NC10-3. doi: 10.7860/JCDR/2015/16207.6791. Epub 2015 Nov 1. PMID: 26675568; PMCID: PMC4668444.
4. Conway RM, Graue GF, Pelayes DE, et al. Conjunctival Carcinoma. American Joint Committee on Cancer (AJCC) AJCC Cancer Staging Manual 8th ed. New York, NY: Springer; 2017.
5. Brierly JD, Gospodarowicz MK, Wittekind C, editors (2017). TNM classification of malignant tumors. 8th ed. Oxford: Wiley Blackwell.
6. Ivanov J, Ugrinski P I sor. Karcinoma na rogovicata, X Internacionalni sekcski sostanok na patolozi na Jugoslavija, 1980, Zbornik na trudovi.129, 1980.
7. Tulvatana W, Bhattarakosol P, Sansopha L, Sipiyarak W, Kowitdamrong E, Paisuntornsug T, Karnsawai S. Risk factors for conjunctival squamous cell neoplasia: a matched case-control study. Br J Ophthalmol. 2003 Apr;87(4):396-8. doi: 10.1136/bjo.87.4.396. PMID: 12642297; PMCID: PMC1771610.
8. Gichuhi S, Sagoo MS. Squamous cell carcinoma of the conjunctiva. Community Eye Health. 2016;29(95):52-53. PMID: 28289320; PMCID: PMC5340104.
9. Bellerive C, Berry JL, Polski A, Singh AD. Conjunctival Squamous Neoplasia: Staging and Initial Treatment. Cornea. 2018 Oct;37(10):1287-1291. doi: 10.1097/ICO.0000000000001651. PMID: 29863543; PMCID: PMC6623971.
10. GarcÃa RLB, Jimenez J, Gubbay C, Castañeda JF, Granados Ã. Squamous cell carcinoma of the conjunctiva. Case report. Int J Surg Case Rep. 2022 Feb;91:106785. doi: 10.1016/j.ijscr.2022.106785. Epub 2022 Jan 24. PMID: 35093703; PMCID: PMC8808077.
11. Ong SS, Vora GK, Gupta PK. Anterior Segment Imaging in Ocular Surface Squamous Neoplasia. J Ophthalmol. 2016;2016:5435092. doi: 10.1155/2016/5435092. Epub 2016 Oct 5. PMID: 27800176; PMCID: PMC5069377.
12. Röck T, Bartz-Schmidt KU, Bramkamp M, Milla J, Bösmüller HC, Röck D. Clinical Management of Squamous Cell Carcinoma of the Conjunctiva. Am J Case Rep. 2020 Feb 1;21:e919751. doi: 10.12659/AJCR.919751. PMID: 32005796; PMCID: PMC7011170.
13. Cicinelli MV, Marchese A, Bandello F, Modorati G. Clinical Management of Ocular Surface Squamous Neoplasia: A Review of the Current Evidence. Ophthalmol Ther. 2018 Dec;7(2):247-262. doi: 10.1007/s40123-018-0140-z. Epub 2018 Jul 20. PMID: 30030703; PMCID: PMC6258579.
14. Nanji AA, Moon CS, Galor A, Sein J, Oellers P, Karp CL. Surgical versus medical treatment of ocular surface squamous neoplasia: a comparison of recurrences and complications. Ophthalmology. 2014 May;121(5):994-1000. doi: 10.1016/j.ophtha.2013.11.017. Epub 2014 Jan 9. PMID: 24411578; PMCID: PMC4011994.
